10 – Molecular machines |
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09 – Photosynthesis |
Architecture of the oxygen-evolving center |
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08 – Structural proteins |
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07 – Drug action |
Model of ligand binding domain of estradiol receptor, binded to drug tamoxifen |
Model of ligand binding domain of serotonin receptor, binded to drug ergotamine |
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06 – Hormone reception |
Model of adrenergic receptor chimeric molecule with lysozyme |
Модель фоторецептора родопсина |
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Model of ligand binding domain of estradiol receptor |
Model of DNA-binding domain of estradiol receptor |
BRI1 plant steroid receptor ectodomain in complex with brassinolide |
05 – Biological signaling |
Acetylcholine receptor from Torpedo marmorata |
Acetylcholine binding protein from Lymnaea stagnalis |
Acetylcholine binding protein in complex with α-cobratoxin |
Insulin from wild boar Sus scrofa |
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Human insulin receptor tyrosine kinase domain |
Human insulin receptor tyrosine kinase domain in complex with peptide substrate and ATP analog |
G-Protein from Rattus norvegicus |
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04 – Biological membranes and transport proteins II |
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1-palmitoyl-2-oleoyl- sn-glycero-3-phosphatidylcholine |
1-palmitoyl-2-oleoyl- sn-glycero-3-phosphatidylcholine |
1-palmitoyl-2-oleoyl- sn-glycero-3-phosphatidylcholine |
1-palmitoyl-2-oleoyl- sn-glycero-3-phosphatidylcholine |
Iron uptake transmembrane protein FepA from Escherichia coli |
Siderophore receptor FauA from Bordetella pertussis |
Maltoporin LamB from Escherichia coli |
α-Hemolysin from Staphylococcus aureus |
Calcium ATPase with bound Ca 2+ ions |
Aquaporin Z from Escherichia coli |
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03 – Storage and transport proteins I |
Heme structure and its bounding with O 2 and apoprotein of myoglobin |
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02 – Nucleic acids |
Structure of cytidine nucleoside |
Hydrogen bonds in B-form of DNA |
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Thymine dimer in DNA b-form |
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01 – Introduction |
Между нуклеосомами находится линкерная ДНК, связанная с гистоном H1, который на модели не показан. Длина межнуклеосомной ДНК составляет 57 пар оснований (обычно 50±10). Гистоны первой нуклеосомы окрашены как на предыдущей модели, на гистонах второй нуклеосомы показаны особенности структуры - α-спирали показаны пурпурным, β-слои - светло-жёлтым. |
Кор гистоновых белков 2x(H2a, H2b, H3, H4) представлен в виде α-спиралей. Гистон H2a показан жёлтым, H2b - красным, H3 - голубым, H4 - зелёным. Сахарофосфатный остов ДНК окрашен светло-жёлтым и розовым, как на предыдущих моделях. Негативная суперспирализованная ДНК длиной 145 нуклеотидных пар делает 1.65 оборота левой спирали. |
Synthetic protein 1VYE used to validate structure prediciton algorithms by X-Ray crystallography |
α-helices only: bacterioferritin from Escherichia coli |
Гомеодомен engrailed из Drosophila melanogaster |
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UDP-N-acetylglucosamine acyltransferase from Escherichia coli |
α-D-mannose specific lectin from snowdrop (Galanthus nivalis) |
ATP-dependent phosphofructokinase from Escherichia coli |
Pilin from Neisseria gonorrhoeae |
Green fluorescent protein from jellyfish Aequorea victoria |